2010年于香港大学获得博士学位；2011 -2014年于中国科学院/深圳大学从事博士后研究；2015入职深圳大学生命与海洋科学学院，先后被聘为讲师、副研究员、副教授、研究员。近年主要从事阿尔茨海默症的发病机制及防治药物研究，在包括Biomaterials, Angew. Chem. Int. Ed., Chem. Commun., Adv. Healthc. Mater.等国际知名期刊发表学术论文20余篇。主持国家自然科学基金2项，深圳市海外高层次人才启动项目、深圳市学科布局项目、深圳市自由探索项目各1项， 获2017年度深圳市自然科学二等奖。2015年入选深圳市海外高层次人才（孔雀计划），2018年入选深圳市高层次人才、深圳市南山区领航人才。
近期发表的论文
1.
Lei Zhang, Penghe Zhao, Caiping Yue, Zhaokui Jin, Qiong Liu,
Xiubo Du
*, Qianjun He*. “
Sustained release of bioactive hydrogen by Pd hydride nanoparticles overcomes Alzheimer's disease”.
Biomaterials
2019 Mar;197:393-404.
(IF=10.3, JCR
一区，
TOP
期刊
)
2.
Mengmeng Ma, Nan Gao,* Yuhuan Sun,
Xiubo Du
,* Jinsong Ren, and Xiaogang Qu*. (2018) “
Redox-Activated Near-Infrared-Responsive Polyoxometalates
Used for Photothermal Treatment of Alzheimer
’
s Disease”
Adv. Healthc. Mater.
doi: 10.1002/adhm.201800320
(IF=6.3, JCR
一区，
TOP
期刊
)
3.
Du XB,
Li HY, Wang XH, Liu Q, Ni JZ and Sun HZ* (2013). "
Kinetics and thermodynamics of metal binding to the N-terminus of a human copper transporter, hCTR1"
Chem. Commun.
49
: 9134-9136
.
(IF=6.8
，
JCR
一区，
TOP
期刊
)
4.
Yongli Xie, Qiong Liu, Lin Zheng, BingTao Wang, Xiaogang Qu, Jiazuan N, Yan Zhang and
Xiubo Du
*. (2018) “Se-Methylselenocysteine Ameliorates Neuropathology and Cognitive Deficits by Attenuating Oxidative Stress and Metal Dyshomeostasis in Alzheimer Model Mice”
Mol. Nutr. Food. Res.
DOI: 10.1002/mnfr.201800107
(
封面文章，
IF=5.2
，
JCR
一区，
TOP
期刊
)
5.
Du XB,
Zheng YB, Wang Z, Chen YJ, Zhou R, Song GL, Ni JZ* and Liu Q* (2014). "
Inhibitory Act of Selenoprotein P on Cu
+
/Cu
2+
-induced tau aggregation and neurotoxicity."
Inorg. Chem
., DOI: 10.1021/ic501788v.
(IF=4.8
，
JCR
一区，
TOP
期刊
)
6.
Du XB,
Wang Z, Zheng YB, Li HP, Ni JZ* and Liu Q* (2014). "
Inhibitory effect of Selenoprotein P on Cu
+
/Cu
2+
-induced Aβ
42
aggregation and toxicity."
Inorg. Chem
., 53 (3): 1672–1678.
(IF=4.8
，
JCR
一区，
TOP
期刊
)
7.
Li X,
Du X
*, Ni J.
Zn
2+
Aggravates Tau Aggregation and Neurotoxicity.
Int J Mol Sci.
2019 Jan 23;20(3). pii: E487.
(IF=4.2, JCR
二区，
TOP
期刊
)
8.
Xiubo Du
#
, Qingqing Shi
#
, Yuxi Zhao, Yongli Xie, Xuexia Li, Qiong Liu, Javed Iqbal, Huajie Zhang, Xukun Liu, and Liming Shen*, “Se-Methylselenocysteine (SMC) Improves Cognitive Deficits by Attenuating Synaptic and Metabolic Abnormalities in Alzheimer’s Mice Model: A Proteomic Study”
ACS Chem Neurosci
2021 Mar 9. doi: 10.1021/acschemneuro.0c00549. (IF=4.5, JCR
二区
)
9.
Caiping Yue
,
Zhifu Shan
,
Yibin Tan
,
Chuangyu Yao
,
Yuanheng Liu
,
Qiong Liu
,
Xiangshi Tan
,
Xiubo Du*
, “His-Rich Domain of Selenoprotein P Ameliorates Neuropathology and Cognitive Deficits by Regulating TrkB Pathway and Zinc Homeostasis in an Alzheimer Model of Mice”,
ACS Chem Neurosci
2020 11(24):4098-4110.
(IF=4.5, JCR
二区
)
10.
Yongli Xie, Yibin Tan, Youbiao Zheng,
Xiubo Du
*, Qiong Liu* (2017). “Ebselen ameliorates β‑amyloid pathology, tau pathology, and cognitive impairment in triple‑transgenic Alzheimer’s disease mice”
J. Biol. Inorg. Chem.
DOI 10.1007/s00775-017-1463-2
(JCR
二区
)
11.
Du XB,
Wang C and Liu Q* (2016). "
Potential Roles of Selenium and Selenoproteins in the Prevention of Alzheimer's Disease."
Curr. Top. Med. Chem
., 2016;16(8):835-48
.
(JCR
二区
)
12.
Du X
B
,
Li H
P,
Wang Z
,
Qiu S
,
Liu Q
* and
Ni J
Z* (2013). “Selenoprotein P and selenoprotein M block Zn
2+
-mediated Aβ
42
aggregation and toxicity.”
Metallomics
5: 861-870.
(JCR
二区
)
13.
Du XB,
Qiu S, Wang Z, Wang RR, Wang C, Tian J and Liu Q* (2014). "
Direct interaction between selenoprotein P and tubulin."
Int. J. Mol. Sci.
15 (6): 10199-10214
. (
JCR
三区
)
2010年于香港大学获得博士学位；2011 -2014年于中国科学院/深圳大学从事博士后研究；2015入职深圳大学生命与海洋科学学院，先后被聘为讲师、副研究员、副教授、研究员。近年主要从事阿尔茨海默症的发病机制及防治药物研究，在包括Biomaterials, Angew. Chem. Int. Ed., Chem. Commun., Adv. Healthc. Mater.等国际知名期刊发表学术论文20余篇。主持国家自然科学基金2项，深圳市海外高层次人才启动项目、深圳市学科布局项目、深圳市自由探索项目各1项， 获2017年度深圳市自然科学二等奖。2015年入选深圳市海外高层次人才（孔雀计划），2018年入选深圳市高层次人才、深圳市南山区领航人才。
