import win32gui, win32ui, win32con, win32api
hwin = win32gui.GetDesktopWindow()
width = win32api.GetSystemMetrics(win32con.SM_CXVIRTUALSCR EEN)
height = win32api.GetSystemMetrics(win32con.SM_CYVIRTUALSCR EEN)
left = win32api.GetSystemMetrics(win32con.SM_XVIRTUALSCRE EN)
top = win32api.GetSystemMetrics(win32con.SM_YVIRTUALSCRE EN)
hwindc = win32gui.GetWindowDC(hwin)
srcdc = win32ui.CreateDCFromHandle(hwindc)
memdc = srcdc.CreateCompatibleDC()
bmp = win32ui.CreateBitmap()
bmp.CreateCompatibleBitmap(srcdc, width, height)
memdc.SelectObject(bmp)
memdc.BitBlt((0, 0), (width, height), srcdc, (left, top), win32con.SRCCOPY)
bmp.SaveBitmapFile(memdc, 'screenshot.bmp')
This code output bmp file size 4mb. I need 100 kb file.

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