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陈怡,副研究员、博士生导师。现任生物医学工程系副主任,生物医学工程国家级实验教学示范中心副主任。中国科协“海智计划”特聘专家,全国纳米技术标准化技术委员会纳米生物医药标准化工作组委员,生物医学工程学会第十一届理事会青委会委员,中国抗癌协会纳米肿瘤学专委会青年委员,江苏省生物医学工程学会教育与科普专委会委员。获得中国科协首届“青年人才托举工程”托举人才;江苏省“双创计划”双创博士;江苏省第十二批科技镇长团“省优秀团员”、“省荣誉团员”;苏州市吴江区人才科技工作特别顾问;苏州独墅湖科教创新区科教骨干人才;“张江高科”奖教金等荣誉与称号。近年来已在 Adv. Mater., Nano Lett., Adv. Func. Mater., ACS Nano, Adv. Sci., Adv. Opt. Mater., ACS Sens., Mater. Today, Biosens. Bioelectron., Chem. Eng. J. 等生物纳米技术与传感器件领域国际权威期刊发表 SCI 收录论文 30 余篇,专著章节 1 篇。

工作经历与教育背景

· 2014.12- 至今 东南大学,生物科学与医学工程学院,副研究员

· 2010.07-2014.07 蒙纳士大学( MONASH University ), 博士

· 2007.09-2010.03 上海交通大学,化学化工学院高分子化学与物理专业,理学硕士

· 2003.09-2007.06 华东理工大学,材料科学与工程学院高分子材料与工程专业,工学学士

研究方向与兴趣:序构增敏感测

· 微纳序构材料及其生物医学检测传感 :功能微纳材料可控合成与修饰,微纳超晶格组装材料,纳米晶 / 聚合物复合组装材料,微纳组装柔性光电材料

· 微纳材料多尺度构效分析与可控性能 :增敏传感构效分析,光电磁等可控性能设计(如表面增强拉曼散射、等离激元共振耦合与杂化、磁驱调控 / 刺激与成像分析等)

· 集成式柔性传感器件与生物医学应用 :化学 / 生物标志物高效捕获检测、特异性识别、分子感应、增敏检测器件,电子皮肤 / 植入式交互器件,磁性微纳器件

人才称号及荣誉

1. 中国科协首届“青年人才托举工程”托举人才( No.YESS20150050

青托人才介绍视频: https://v.douyin.com/LpvTVG8/

2. 江苏省“双创计划”双创博士

3. 江苏省委组织部第十二批科技镇长团“省优秀团员”、“省荣誉团员”

科研项目

1. 国家自然科学基金面上项目, 2025/1-2028/12 ,主持

2. 国家自然科学基金青年基金, 2016/1-2018/12 ,主持

3. KJ GF 科技创新特区项目 - 子课题, 2020/12-2022/12 ,主持

4. 江苏省自然科学基金面上项目, 2023/7-2026/6 ,主持

5. 苏州市基础研究计划前沿技术研究项目, 2023/7-2026/6 ,主持

6. 苏州市重点产业技术创新前瞻性应用研究项目, 2019/7-2021/6 ,主持

7. 苏州市应用基础研究项目, 2015/7-2018/7 ,主持

8. 横向技装项目, *** 2023/9-2024/9 ,主持

9. 国家重点研发计划纳米前沿重点专项( 2021YFA1201400 ), 2021/12-2026/11 ,参与

10. 国家自然科学基金重点项目( 11734005 ), 2018/1-2022/12 ,参与

11. 国家自然科学基金重点项目( 92163213 ), 2022/1-2025/12 ,参与

教学与人才培养

1. 本科课程:《生物材料创新与前沿》(课程思政示范课),《无机化学》,《分析化学》

2. 研究生课程:《先进材料创制与前沿》,《纳米科学技术引论》,《功能材料创制和应用(全英文 - 东蒙)》,《生物电子学(全英文 - 东蒙)》,《健康数据科学最新进展(参讲,全英文 - 东蒙)》

3. 主持校级本科及研究生教改项目 3

4. 2019 年江苏省优秀本科毕业论文二等奖(王鲜宣); 2023 东大优秀硕士论文指导老师(张恒); 2023 东大学习优秀生“优秀导师”(杨成)

5. 全国生物医学工程创新设计竞赛三等奖(杨成等; 2023&2024 连续两届获奖)

代表性论文及专著( SELECTED PUBLICATIONS

(1). Zhang, H.; Zhang, H. Q.; Sikdar, D.; Liu, X. C.; Yang, Z. R.; Cheng, W. L.; Chen, Y.* , Jellyfish-like Gold Nanowires as FlexoSERS Sensors for Sweat Analysis. Nano Letters 2024, accepted.

(2). Zhang, H.; Lin, F.; Chen, G.; Yang, C.; Zhang, H. Q.; Yan, M.; Li, H.; Wang, X.; Cheng, W. L.; Chen, Y.* , Intrinsically stretchable jellyfish-like gold nanowires film as multifunctional wearable chemical and physical sensors. Chemical Engineering Journal 2024, 490, 151798.

(3). Gao, M. M.; Zhang, D.*; Chen, Y.* ; Zhang, Y.; Wang, Z.; Wang, X.; Li, S.; Guo, Y.; Webb, G. I.; Nguyen, A. T. N.; May, L.; Song, J.*, GraphormerDTI: A graph transformer-based approach for drug-target interaction prediction. Computers in Biology and Medicine 2024, 173, 108339.

(4). Zhang, H.; Lin, F. E.; Cheng, W. L. ; Chen, Y.* ; Gu, N.*, Hierarchically Oriented Jellyfish-like Gold Nanowires Film for Elastronics. Advanced Functional Materials , 2023, 2209760.

(5). Chen, Y.* ; Bai, Y.; Wang, X.; Zhang, H.; Zheng, H.; Gu, N.*, Plasmonic/magnetic nanoarchitectures: From controllable design to biosensing and bioelectronic interfaces. Biosensors and Bioelectronics , 2023, 219, 114744.

(6). Zhang, H.; Wang, R.; Sikdar, D.; Wu, L. Y.; Sun, J.; Gu, N.; Chen, Y.* , Plasmonic Superlattice Membranes Based on Bimetallic Nano-Sea Urchins as High-Performance Label-Free Surface-Enhanced Raman Spectroscopy Platforms. ACS Sensors , 2022, 7, 2, 622-631

(7). Chen, Y.* ; Yin, H.; Sikdar, D.; Yan, L.; Zhou, Z.; Sun, J. * ; Wang, C., Gold Nanopolyhedron-Based Superlattice Sheets as Flexible Surface-Enhanced Raman Scattering Sensors for Detection of 4-Aminothiophenol. ACS Applied Nano Materials 2021, 4, 12498-12505.

(8). Chen, Y. ; Yin, H.; Sikdar, D.; Liu, H.; Zhu, Q.; Yao, G.; Qi, H.; Gu, N.*, Multiscale Patterned Plasmonic Arrays for Highly Sensitive and Uniform SERS Detection. Advanced Materials Interfaces 2020, 7, 2000248

(9). Chen, Y. ; Liu, H.; Yin, H.; Zhu, Q.; Yao, G.; Gu, N.*, Hierarchical Fabrication of Plasmonic Superlattice Membrane by Aspect-Ratio Controllable Nanobricks for Label-Free Protein Detection. Frontiers in Chemistry 2020, 8:307

(10). Chen, Y.* ; Bai, Y.; Zhang, H.; Zhou, Z., Plasmonic nanoassemblies for surface-enhanced Raman scattering-based biodetection and biomedical theranostics. STEMedicine 2022, 3 (4), e147

(11). Si, K. J.; Chen, Y. ; Shi, Q.; Cheng, W. L. * , Nanoparticle Superlattices: The Roles of Soft Ligands. Advanced Science 2018, 5 (1) , 1700179.

(12). Si, K. J.; Chen, Y. ; Cheng, W. L. * Plasmene Origami. Materials Today . 2016, 19 (6) , 363-364.

(13). Chen, Y. ; Si, K. J.; Sikdar, D.; Tang, Y.; Premaratne, M.; Cheng, W. L. * , Ultrathin Plasmene Nanosheets as Soft and Surface-Attachable SERS Substrates with High Signal Uniformity. Advanced Optical Materials 2015, 3 , 919-924.

(14). Chen, Y. ; Ouyang, Z.; Gu, M.; Cheng, W. L. * , Mechanically Strong, Optically Transparent, Giant Metal Superlattice Nanomembranes From Ultrathin Gold Nanowires. Advanced Materials 2013, 25 , 80-85.

(15). Chen, Y. ; Cheng, W. L. * , DNA-based plasmonic nanoarchitectures: from structural design to emerging applications. Wiley Interdisciplinary Reviews - Nanomedicine and Nanobiotechnology 2012, 4 , 587-604.

(16). Chen, Y. ; Fu, J.; Ng, K. C.; Tang, Y.; Cheng, W. L. * , Free-Standing Polymer-Nanoparticle Superlattice Sheets Self-Assembled at the Air Liquid Interface. Crystal Growth & Design 2011, 11 , 4742-4746.

(17). Chen, Y. ; Ng, K. C.; Yan, W.; Tang, Y.; Cheng, W. L. * , Ultraflexible plasmonic nanocomposite aerogel. RSC Advances 2011, 1 , 1265-1270.

(18). Chen, Y. ; Pang, X.-H.; Dong, C.-M. * , Dual Stimuli-Responsive Supramolecular Polypeptide-Based Hydrogel and Reverse Micellar Hydrogel Mediated by HostGuest Chemistry. Advanced Functional Materials 2010, 20 , 579-586.

(19). Chen, Y. ; Dong, C.-M. * , pH-Sensitive Supramolecular Polypeptide -Based Micelles and Reverse Micelles Mediated by Hydrogen-Bonding Interactions or Host−Guest Chemistry: Characterization and In Vitro Controlled Drug Release. Journal of Physical Chemistry B 2010, 114 , 7461-7468.

(20). Si, K. J.; Sikdar, D.; Chen, Y. ; Xu, Z.; Tang, Y.; Xiong, W.; Guo, P.; Zhang, S.; Lu, Y.; Bao, Q.; Zhu, W.; Premaratne, M.; Cheng, W. L. * , Giant Plasmene Nanosheets, Nanoribbons, and Origami. ACS Nano 2014, 8 , 11086-11093.

(21). Su, B.; Wu, Y.; Tang, Y.; Chen, Y. ; Cheng, W. L. * ; Jiang, L., Free-Standing 1D Assemblies of Plasmonic Nanoparticles. Advanced Materials 2013, 25 , 3968-3972.

(22). Tang, Y.; Gong, S.; Chen, Y. ; Yap, L. W.; Cheng, W. L. * , Manufacturable Conducting Rubber Ambers and Stretchable Conductors from Copper Nanowire Aerogel Monoliths. ACS Nano 2014, 8 , 5707-5714.

(23). Gong, S.; Schwalb, W; Wang, Y. W.; Chen, Y. ; Tang, Y.; Si, J.; Shirinzadeh, B.; Cheng, W. L. * , A wearable and highly sensitive pressure sensor with ultrathin gold nanowires. Nature Communications 2014, 5 :3132.

(24). Xie, S. Y., Chen, Y. , Ouyang, Z., Jia, B. H., Cheng, W. L. * , Gu, M. * , Transparent gold nano-membranes for the enhanced light trapping of the indium tin oxide films. Optical Materials Express 2014, 4 , 321-328.

(25). Peng, S.-M.; Chen, Y. ; Hua, C.; Dong, C.-M. * , Dendron-like Polypeptide/Linear Poly(ethylene oxide) Biohybrids with Both Asymmetrical and Symmetrical Topologies Synthesized via the Combination of Click Chemistry and Ring-Opening Polymerization. Macromolecules 2008, 42 , 104-113.

(26). Yang, W. J.; Chen, Y. ; Cheng, W. L., Book chapter in Handbook of Nanomaterials Properties, Springer , 3879 words, ISBN 978-3-642-31107-9, 2014.

专利

(1). 陈怡,刘晃,殷豪景,顾宁 , “一种基于金银纳米砖的可控微纳阵列的构建方法及其应用”,中国发明专利( ZL201811001014.X

(2). 陈怡,周正,严玲琳,时画,顾宁 , “一种基于金属纳米粒子和微凝胶的复合药物载体及其应用”,中国发明专利( ZL201810999323.4

(3). 陈怡,张恒,顾宁,“一种可拉伸仿生簇状金纳米线薄膜及制备方法与应用”,中国发明专利( ZL202210058000.1

(4). 陈怡,张恒,吴临远,顾宁 , “一种异质贵金属海胆型纳米晶体、其二维超晶格薄膜及其制备方法和应用” , 中国发明专利 , ZL202011404247.1

(5). 陈怡,张恒,顾宁,“基于金纳米森林结构的柔性可拉伸 SERS 基底及其制法和应用”,中国发明专利( 2023118461938

(6). 陈怡,张雪,顾宁,“一种基于梭型纳米晶体的 SERS 检测器及其制法和应用”,中国发明专利( 202210479704.6

(7). 陈怡,叶悠扬,张恒,顾宁,“金银铂核壳镂空纳米砖及其制备方法与应用”,中国发明专利,( 202110290301.2

(8). 陈怡,殷豪景,刘晃,顾宁 , “一种柔性可转移型表面增强拉曼检测基底及其制备方法和应用”,中国发明专利( 201811146011.5

(9). 陈怡,刘晃,殷豪景,顾宁 , “一种二维柔性贵金属纳米粒子超晶格薄膜及其构建方法和应用”,中国发明专利( 201811090882.X

本小组从属于江苏省生物材料与器件重点实验室(顾宁院士纳米组),每年招收博士生 1 名,学硕 2 / 专硕 3 名,欢迎同学们联系并加入课题组。

同时,欢迎报考东南大学 - 蒙纳士大学联合研究生院生物与医药(生物纳米技术)及电子信息(健康数据)联培专硕学位;欢迎计划出国留学深造的同学与我联系,也欢迎报考 东南大学 - 蒙纳士大学联合研究院联合培养 博士 项目

Positions for postgraduate students (Master and PhD) and Postdoc are available in our group. We are looking for highly-motivated Master/PhD candidates to join us. The positions are open for students with background in Chemistry, Chemical Engineering, Materials Engineering, Materials science or Biological Engineering, etc. Please send inquiries along with a detailed CV to Prof. Yi Chen (yichen@seu.edu.cn). Experiences in Nanomaterials, Polymer science and engineering, Self-assembled Nanomaterials, Theranostics, Surface chemistry, Nanofabrication, Biology, Bioelectronics is a plus.



通讯地址( CONTACT INFO

东南大学九龙湖校区医工楼 1201 / 丁家桥校区小蓝楼三楼

School of Biological Science and Medical Engineering

Jiangsu Key Laboratory for Biomaterials and Devices

SEU-MONASH Joint Graduate School (Suzhou)

Southeast University

C/O: Rm 1201, BME Building, Jiulonghu Campus, Nanjing | 211102

E-mail yichen@seu.edu.cn