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PHP Warning: PHP Startup: Unable to load dynamic library '/usr/local/lib/php/extensions/no-debug-non-zts-20090626/ixed.5.2.lin' - /usr/local/lib/php/extensions/no-debug-non-zts-20090626/ixed.5.2.lin: cannot open shared object file: No such file or directory in Unknown on line 0

What does that mean?

It means there is an extension=... or zend_extension=... line in one of your php configuration files (php.ini, or another close to it) that is trying to load that extension : ixed.5.2.lin

Unfortunately that file or path doesn't exist or the permissions are incorrect.

If you're on Linux, you can find all loaded configuration files by typing this in shell:

php -r "print phpinfo();" | grep ".ini"
UPDATE:
As mentioned in comments, this can be even more accurate:
php -i | grep ini
                Just keep in mind that the php command line can use different phi.ini files from php web modules. This should get you closer at least though.
– beporter
                May 19, 2022 at 19:05
phpStom with XAMPP 
TL;DR Except from verifying that the files exist, you might need to add the drive letter to some records in your php.ini file
I suddenly started having a problem using phpStorm 7 for debugging php with xampp and xdebug. When trying to set intellij interperter to be xampps php I got a lot of the warnings like the one in the question, for example: 
  
Unable to load dynamic library '/xampp/php/ext/php_bz2.dll'
For some reason I had to add my drive letter to the records of extension_dir and browscap in the php.ini file:
extension_dir = "\xampp\php\ext"
browscap = "\xampp\php\extras\browscap.ini"
extension_dir = "e:\xampp\php\ext"
browscap = "e:\xampp\php\extras\browscap.ini"
                Using extension_dir = "ext" works when you run from cmd, but when you run from Apache you probably need an absolute path (with drive letter etc).
– Nux
                Dec 2, 2020 at 14:46
If you just want to make the error disappear, and you don't need the extension, then by all means comment the line out in php.ini. But if you actually want to fix the problem here is some additional info.
There are various causes for this based on the exact module, but there are also some general guidelines.
Open phpinfo() and look for extension_dir under the Core section. This is where your modules should be located.
  
For instance, /usr/lib/php/modules for Unix/Linux.
If the file does in fact exist, make sure permissions are adequate.
If the file does not exist, use the resources below to install it.
Installation on *nix (PEAR)

Installation of extensions on Windows
                I'm trying to install through this pear module but when I run perl install <module> I got Can't open perl script "install": File or Directory not found
– Fnr
                Dec 3, 2016 at 14:28
Loading .dll in Linux
I've encountered this warning message while I was trying to install a php-extension via the php.ini file;
until I figured out that you cannot load .dll extensions in Linux, 
but you have to comment the extensions that you want to import ;extension= ... .dll and install it correctly via sudo apt-get install php-...
note: ... is the extension name you want to enable.
                Exactly, for me it was simply missing module installation - I was installing phpPgAdmin and what I needed to install explicitly was sudo apt install php-pgsql and php-version-specific sudo apt install php7.1-pgsql (change 7.1 to your php version)
– jave.web
                Aug 28, 2019 at 16:42
Note that you can also get this error if your PHP library doesn't have the "other" directory opening permission. In my particular case, I noticed this when using php -l to syntax check a script in my text editor. This meant that since my account was called "volomike", that account didn't have permission to run the libraries that the php command relied upon.
For instance, on Ubuntu 14.04, I had PHP5 installed automatically into the path /usr/lib/php5/20121212+lfs. However, because I was working in C++ in building some shared objects, I messed around with the directory permissions and screwed things up such that non-root accounts did not have the directory execute (directory open) permissions to view /usr/lib/php5/20121212+lfs. So, I typed the following command to rectify that problem:
sudo chmod o+x /usr/lib/php5/20121212+lfs.
Now when I do php -l example.php as a non-root user, it never gives me this "Unabled to load dynamic library" problem anymore.
                This was the exact solution for me, using Ubuntu 16.10. Make sure that you change the extension "extension" to .so when using Linux (standard config was giving me .dll)
– mroesler
                Oct 18, 2016 at 9:41
I had the same problem on XAMPP for Windows when I try to install composer.
I did php -v and php throwing error :
  
Unable to load dynamic library '/xampp/php/ext/php_bz2.dll'
It took me a while until I realized that I need to setup my XAMPP. So I run setup_xampp.bat and php return to works like a charm.
I had this error on a number of modules when I had been running different versions of PHP side by side on my server. To sort this out, I needed to install the packages it couldn't find for that specific PHP version. So, for example, if I saw:-
PHP Warning:  PHP Startup: Unable to load dynamic library '/usr/lib/php/20160303/xml.so'
I would install the library for the PHP version specifically:-
sudo apt-get install php7.1-xml
And then restart Apache. Fixed it for me. You can check your version like this:-
php -v
just open your current_xampp_containing_drive:\xampp(default_xampp_folder)\php\php.ini in texteditor (like notepad++)
now just find - is the current_xampp_containing_drive:\xampp exist?
if not then find the "extension_dir" and get the drive name(c,d or your desired drive) like.
  
extension_dir="F:\xampp731\php\ext" (here finded_drive_name_from_the_file is F)
again replace with finded_drive_name_from_the_file:\xampp with current_xampp_containing_drive:\xampp and save.
now again start the composer installation progress, i think your problem will be solved.
What I did was; 
1 - I first find out what version of PHP I am using thru the function phpinfo()
    phpinfo();
2 - From there you will find the location of your configuration(php.ini) file
3 - Open that file
4 - Comment out the line similar to the image below
  
This might be a different value but it should be related to extension.
  I am no expert but this process helped me solved similar problem.
                To check on server thread-safe config see phpinfo() and thread-safety enabled/disabled.  Had same error in reverse, downloaded nts when configured for ts.
– user2711811
                Jul 22, 2020 at 20:23
After Windows 10 XAMPP now I installed LAMPP (XAMPP) on Ubuntu. Windows XAMPP had a lot less to configure compare to MAC (iOS) but now with Linux Ubuntu I had a few more since there are more going in Linux (a good thing). 
I confused and activated mysqli.dll (and mysql.dll: erase "#" in /etc/php/7.2/cli/php.ini
I started to get the PHP Warning:  PHP Startup: Unable to load dynamic library message related to dll. I commented out mysql(and i).dll in the same file but the message didn't go away up until I commented out " " in /opt/lampp/etc/php.ini.
Looks like XAMPP reads php.ini file from /etc/php/7.2/cli and makes modification in php.ini of /opt/lampp/etc. (;extension=php_pdo_mysql.dll after ";" restarted Apache and no more any message.
'C:/PHP/5.2.13/ext\php_mcrypt1.dll'
I'd say there's some typo on your php.ini (the extra 1). Perhaps you're loading a different php.ini from what you expect (see the output of php.ini to make sure).
Other than that make sure that php_mcrypt.dll and PHP:
Were linked to the same VC runtime library (typically msvcrt.dll for VC6 or msvcrt90.dll for VC9) – use e.g. the dependency walker for this
Are both debug builds or both release builds
Both have ZTS enabled or ZTS disabled
For libraries that depend on further libraries (DLLs), make sure they are available (e.g. in the same directory as the extension)
PHP should give you meaning errors if any of the first three conditions above is not satisfied, but I wrote those anyway because I'm not sure for PHP 5.2.
Unable to load dynamic library ''

C:\xampp\php\ext\php_.dll (The specified module could not be found.)
I solved by commenting out

C:\xampp\php\php.ini

;extension=
I had the same problem when I tried to use php with sql server, when I added the sqlsrv libraries ... it gave me the error, after several days of researching there, I understood that microsoft does not support x64 in this case so what I did was install laragon x86 and use the corresponding libraries. I hope it helps with something
        
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