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According to the official Python.NET documention I'm supposed to install it using pip install pythonnet , this gives me an error however. I have upgraded the following packages trying to fix it:

  • setuptools
  • wheel
  • This however didn't fix it and it's throwing some errors.

    Collecting pythonnet
      Using cached pythonnet-2.5.2.tar.gz (1.9 MB)
      Preparing metadata (setup.py) ... done
    Requirement already satisfied: pycparser in c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages (from pythonnet) (2.21)
    Building wheels for collected packages: pythonnet
      Building wheel for pythonnet (setup.py) ... error
      ERROR: Command errored out with exit status 1:
       command: 'c:\users\kiron\appdata\local\programs\python\python310\python.exe' -u -c 'import io, os, sys, setuptools, tokenize; sys.argv[0] = '"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"'; __file__='"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"';f = getattr(tokenize, '"'"'open'"'"', open)(__file__) if os.path.exists(__file__) else io.StringIO('"'"'from setuptools import setup; setup()'"'"');code = f.read().replace('"'"'\r\n'"'"', '"'"'\n'"'"');f.close();exec(compile(code, __file__, '"'"'exec'"'"'))' bdist_wheel -d 'C:\Users\kiron\AppData\Local\Temp\pip-wheel-teu689ee'
           cwd: C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\
      Complete output (91 lines):
      running bdist_wheel
      running build
      running build_ext
      Checking for updates from https://www.nuget.org/api/v2/.
      Currently running NuGet.exe 4.1.0.
      Updating NuGet.exe to 6.0.0.
      Update successful.
      Cannot find the specified version of msbuild: '14'
      MSBuild auto-detection: using msbuild version '16.11.2.50704' from 'C:\Program Files (x86)\Microsoft Visual Studio\2019\Community\MSBuild\Current\bin'.
      Restoring NuGet package NUnit.ConsoleRunner.3.11.1.
      Restoring NuGet package NUnit.3.12.0.
      Adding package 'NUnit.3.12.0' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
      Adding package 'NUnit.ConsoleRunner.3.11.1' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
      Added package 'NUnit.ConsoleRunner.3.11.1' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
      Restoring NuGet package System.ValueTuple.4.5.0.
      Adding package 'System.ValueTuple.4.5.0' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
      Added package 'NUnit.3.12.0' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
      Restoring NuGet package UnmanagedExports.1.2.7.
      Adding package 'UnmanagedExports.1.2.7' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
      Added package 'System.ValueTuple.4.5.0' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
      Added package 'UnmanagedExports.1.2.7' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
      NuGet Config files used:
          C:\Users\kiron\AppData\Roaming\NuGet\NuGet.Config
          C:\Program Files (x86)\NuGet\Config\Microsoft.VisualStudio.Offline.config
      Feeds used:
          C:\Users\kiron\.nuget\packages\
          https://api.nuget.org/v3/index.json
          https://packages.stride3d.net/nuget
          C:\Program Files (x86)\Microsoft SDKs\NuGetPackages\
      Installed:
          4 package(s) to packages.config projects
      Traceback (most recent call last):
        File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\tools\geninterop\geninterop.py", line 396, in <module>
          sys.exit(main())
        File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\tools\geninterop\geninterop.py", line 357, in main
          python_h = preprocess_python_headers()
        File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\tools\geninterop\geninterop.py", line 238, in preprocess_python_headers
          for line in _check_output(cmd).splitlines():
        File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\tools\geninterop\geninterop.py", line 46, in _check_output
          output = subprocess.check_output(*args, **kwargs)
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\subprocess.py", line 420, in check_output
          return run(*popenargs, stdout=PIPE, timeout=timeout, check=True,
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\subprocess.py", line 501, in run
          with Popen(*popenargs, **kwargs) as process:
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\subprocess.py", line 966, in __init__
          self._execute_child(args, executable, preexec_fn, close_fds,
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\subprocess.py", line 1435, in _execute_child
          hp, ht, pid, tid = _winapi.CreateProcess(executable, args,
      FileNotFoundError: [WinError 2] The system cannot find the file specified
      Traceback (most recent call last):
        File "<string>", line 1, in <module>
        File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\setup.py", line 630, in <module>
          setup(
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\__init__.py", line 155, in setup
          return distutils.core.setup(**attrs)
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\core.py", line 148, in setup
          return run_commands(dist)
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\core.py", line 163, in run_commands
          dist.run_commands()
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\dist.py", line 967, in run_commands
          self.run_command(cmd)
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\dist.py", line 986, in run_command
          cmd_obj.run()
        File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\setup.py", line 612, in run
          return bdist_wheel.bdist_wheel.run(self)
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\wheel\bdist_wheel.py", line 299, in run
          self.run_command('build')
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\cmd.py", line 313, in run_command
          self.distribution.run_command(command)
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\dist.py", line 986, in run_command
          cmd_obj.run()
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\command\build.py", line 135, in run
          self.run_command(cmd_name)
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\cmd.py", line 313, in run_command
          self.distribution.run_command(command)
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\dist.py", line 986, in run_command
          cmd_obj.run()
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\command\build_ext.py", line 339, in run
          self.build_extensions()
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\command\build_ext.py", line 448, in build_extensions
          self._build_extensions_serial()
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\command\build_ext.py", line 473, in _build_extensions_serial
          self.build_extension(ext)
        File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\setup.py", line 302, in build_extension
          subprocess.check_call([sys.executable, geninterop, interop_file])
        File "c:\users\kiron\appdata\local\programs\python\python310\lib\subprocess.py", line 369, in check_call
          raise CalledProcessError(retcode, cmd)
      subprocess.CalledProcessError: Command '['c:\\users\\kiron\\appdata\\local\\programs\\python\\python310\\python.exe', 'tools\\geninterop\\geninterop.py', 'src\\runtime\\interop310.cs']' returned non-zero exit status 1.
      ----------------------------------------
      ERROR: Failed building wheel for pythonnet
      Running setup.py clean for pythonnet
    Failed to build pythonnet
    Installing collected packages: pythonnet
        Running setup.py install for pythonnet ... error
        ERROR: Command errored out with exit status 1:
         command: 'c:\users\kiron\appdata\local\programs\python\python310\python.exe' -u -c 'import io, os, sys, setuptools, tokenize; sys.argv[0] = '"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"'; __file__='"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"';f = getattr(tokenize, '"'"'open'"'"', open)(__file__) if os.path.exists(__file__) else io.StringIO('"'"'from setuptools import setup; setup()'"'"');code = f.read().replace('"'"'\r\n'"'"', '"'"'\n'"'"');f.close();exec(compile(code, __file__, '"'"'exec'"'"'))' install --record 'C:\Users\kiron\AppData\Local\Temp\pip-record-xe4ba95q\install-record.txt' --single-version-externally-managed --compile --install-headers 'c:\users\kiron\appdata\local\programs\python\python310\Include\pythonnet'
             cwd: C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\
        Complete output (6 lines):
        usage: setup.py [global_opts] cmd1 [cmd1_opts] [cmd2 [cmd2_opts] ...]
           or: setup.py --help [cmd1 cmd2 ...]
           or: setup.py --help-commands
           or: setup.py cmd --help
        error: option --single-version-externally-managed not recognized
        ----------------------------------------
    ERROR: Command errored out with exit status 1: 'c:\users\kiron\appdata\local\programs\python\python310\python.exe' -u -c 'import io, os, sys, setuptools, tokenize; sys.argv[0] = '"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"'; __file__='"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"';f = getattr(tokenize, '"'"'open'"'"', open)(__file__) if os.path.exists(__file__) else io.StringIO('"'"'from setuptools import setup; setup()'"'"');code = f.read().replace('"'"'\r\n'"'"', '"'"'\n'"'"');f.close();exec(compile(code, __file__, '"'"'exec'"'"'))' install --record 'C:\Users\kiron\AppData\Local\Temp\pip-record-xe4ba95q\install-record.txt' --single-version-externally-managed --compile --install-headers 'c:\users\kiron\appdata\local\programs\python\python310\Include\pythonnet' Check the logs for full command output.
    

    Now, I do see that it has something to do with my VS2019 installation, but I cannot tell what the issue is. Should I perhaps do a fresh reinstall of VS2019? And if so, what workloads and individual components should I install?

    EDIT 1

    I have just done a fresh reinstall of VS2019, with the following workloads, their installation detailsand the following individual components:

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