The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Share Capsule retention occurred in 1.4% of our patients (14/1000). Eleven patients failed to pass the capsule because of nonsteroidal anti-inflammatory drug (NSAID) enteropathy (diaphragm disease). One patient had capsule retention from an obstructing carcinoid tumor. Metastatic ovarian cancer with invasion of the ileum was the cause of retention in another patient. One patient who did not have surgical removal of the capsule because of loss of follow-up had retention caused by a small-bowel tumor suspicious for carcinoid tumor on CT enterography. All patients remained "asymptomatic" from the retained capsules. Thirteen patients underwent elective partial small-bowel resection and capsule removal. No deaths were associated with these surgeries. Eleven patients recovered promptly, whereas 2 patients had mild postoperative ileus. Retention of the capsule endoscope appears to be infrequent. The most common cause is diaphragm disease resulting from NSAIDs in this study population. In most cases, capsule retention is asymptomatic, and it usually leads to surgical removal, which appears safe and also identifies and treats the underlying small-bowel condition. Van Weyenberg SJ, et al. Gastrointest Endosc. 2010 Mar;71(3):535-41. doi: 10.1016/j.gie.2009.10.029. Gastrointest Endosc. 2010. PMID: 20189512 Cheon JH, et al. Endoscopy. 2007 Dec;39(12):1046-52. doi: 10.1055/s-2007-966978. Endoscopy. 2007. PMID: 18072054 Atay O, et al. J Pediatr Gastroenterol Nutr. 2009 Aug;49(2):196-201. doi: 10.1097/MPG.0b013e3181926b01. J Pediatr Gastroenterol Nutr. 2009. PMID: 19561547 Review. Singeap AM, et al. Eur J Gastroenterol Hepatol. 2011 Oct;23(10):886-90. doi: 10.1097/MEG.0b013e328349efa4. Eur J Gastroenterol Hepatol. 2011. PMID: 21811157 Karagiannis S, et al. Scand J Gastroenterol. 2009;44(10):1158-65. doi: 10.1080/00365520903132039. Scand J Gastroenterol. 2009. PMID: 19606392 Review. Singla N, et al. Endosc Int Open. 2023 Jun 29;11(6):E623-E628. doi: 10.1055/a-2096-2453. eCollection 2023 Jun. Endosc Int Open. 2023. PMID: 37614640 Free PMC article. Lu T, et al. Sensors (Basel). 2023 Mar 9;23(6):2991. doi: 10.3390/s23062991. Sensors (Basel). 2023. PMID: 36991702 Free PMC article. Review. Gala D, et al. Cureus. 2022 Dec 20;14(12):e32735. doi: 10.7759/cureus.32735. eCollection 2022 Dec. Cureus. 2022. PMID: 36686135 Free PMC article. Parigi TL, et al. J Clin Med. 2022 Feb 7;11(3):872. doi: 10.3390/jcm11030872. J Clin Med. 2022. PMID: 35160322 Free PMC article. Review. Tayyub MU, et al. Case Rep Gastroenterol. 2021 Nov 15;15(3):948-953. doi: 10.1159/000519551. eCollection 2021 Sep-Dec. Case Rep Gastroenterol. 2021. PMID: 34949980 Free PMC article.