相关文章推荐
不拘小节的黄花菜  ·  张锴琦·  6 月前    · 
朝气蓬勃的豆腐  ·  安装Genymotion ...·  7 月前    · 
求醉的杯子  ·  Meta千亿参数大模型OPT-IML「升级版 ...·  1 年前    · 
年轻有为的橡皮擦  ·  神级外卖小哥漫画｜官方在线漫画全集-快看漫画·  1 年前    · 
腹黑的葡萄  ·  以美寓真的哲性写作 _光明网·  1 年前    · 
Code  ›  肽：MHC四聚体为基础的抗原表位特异性的T细胞的富集 (文章) | JoVE
cell 特异性 抗原表位 抗原决定簇
https://www.jove.com/t/4420/peptidemhc-tetramer-based-enrichment-of-epitope-specific-t-cells?language=Chinese
聪明的冰棍
3 月前
EN - English CN - 中文 DE - Deutsch ES - Español KR - 한국어 IT - Italiano FR - Français PT - Português JA - 日本語 TR - Türkçe
Close
Research
  • Knutson, K. L., dela Rosa, C., Disis, M. L. Laboratory analysis of T-cell immunity. Front Biosci . 11 , 1932-1944 (2006).
  • Kearney, E. R., Pape, K. A., Loh, D. Y., Jenkins, M. K. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity . 1 , 327-339 (1994).
  • Moon, J. J. Tracking epitope-specific T cells. Nat Protoc . 4 , 565-581 (2009).
  • Hataye, J., Moon, J. J., Khoruts, A., Reilly, C., Jenkins, M. K. Naive and memory CD4+ T cell survival controlled by clonal abundance. Science . 312 , 114-116 (2006).
  • Marzo, A. L. Initial T cell frequency dictates memory CD8+ T cell lineage commitment. Nat Immunol . 6 , 793-799 (2005).
  • Davis, M. M., Altman, J. D., Newell, E. W. Interrogating the repertoire: broadening the scope of peptide-MHC multimer analysis. Nature reviews. Immunology . 11 , 551-558 (2011).
  • Moon, J. J. Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. Immunity . 27 , 203-213 (2007).
  • Seah, S. G. The linear range for accurately quantifying antigen-specific T-cell frequencies by tetramer staining during natural immune responses. European Journal of Immunology . 41 , 1499-1500 (2011).
  • Obar, J. J., Khanna, K. M., Lefrancois, L. Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection. Immunity . 28 , 859-869 (2008).
  • Daniels, M. A., Jameson, S. C. Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers. J Exp Med . 191 , 335-346 (2000).
  • Pittet, M. J. Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells. Journal of Immunology . 171 , 1844-1849 (2003).
  • Choi, E. M. High avidity antigen-specific CTL identified by CD8-independent tetramer staining. Journal of Immunology . 171 , 5116-5123 (2003).
  • Chu, H. H. Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire. Proc Natl Acad Sci U S A . 106 , 11241-11245 (2009).
  • Chu, H. H., Moon, J. J., Kruse, A. C., Pepper, M., Jenkins, M. K. Negative Selection and Peptide Chemistry Determine the Size of Naive Foreign Peptide-MHC Class II-Specific CD4+ T Cell Populations. J Immunol . 185 , 4705-4713 (2010).
  • Legoux, F. Impact of TCR reactivity and HLA phenotype on naive CD8 T cell frequency in humans. J Immunol . 184 , 6731-6738 (2010).
  • Alanio, C., Lemaitre, F., Law, H. K., Hasan, M., Albert, M. L. Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies. Blood . 115 , 3718-3725 (2010).
  • Kwok, W. W. Frequency of Epitope-Specific Naive CD4+ T Cells Correlates with Immunodominance in the Human Memory Repertoire. Journal of Immunology . 188 , 2537-2544 (2012).
  • Jenkins, M. K., Chu, H. H., McLachlan, J. B., Moon, J. J. On the composition of the preimmune repertoire of T cells specific for Peptide-major histocompatibility complex ligands. Annu Rev Immunol . 28 , 275-294 (2010).
  • Matechak, E. O., Killeen, N., Hedrick, S. M., Fowlkes, B. J. MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent. Immunity . 4 , 337-347 (1996).
  • Burchill, M. A. Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire. Immunity . 28 , 112-121 (2008).
  • Pepper, M. Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells. Nature Immunology . 11 , 83-89 (2010).
    • Peptide:MHC Tetramer-based Enrichment Epitope-specific T Cells T Cell Antigen Receptor Specificity Functional Response Proliferation Cytokine Production Activation Markers TCR Transgenic Adoptive Transfer Model Monoclonal T Cells Histocompatible Hosts Congenic Marker Antibody Experimental Artifacts Functional Heterogeneity Polyclonal Population
     
    推荐文章
    不拘小节的黄花菜  ·  张锴琦
    6 月前
    朝气蓬勃的豆腐  ·  安装Genymotion android模拟器 - 飘飘雪 - 博客园
    7 月前
    求醉的杯子  ·  Meta千亿参数大模型OPT-IML「升级版」来了，完整模型和代码公布！-腾讯云开发者社区-腾讯云
    1 年前
    年轻有为的橡皮擦  ·  神级外卖小哥漫画｜官方在线漫画全集-快看漫画
    1 年前
    腹黑的葡萄  ·  以美寓真的哲性写作 _光明网
    1 年前
    今天看啥   ·   Py中国   ·   codingpro   ·   藏经阁   ·   小百科   ·   link之家   ·   卧龙AI搜索
    删除内容请联系邮箱 2879853325@qq.com
    Code - 代码工具平台
    © 2024 ~ 沪ICP备11025650号